IJ Some 1,4-dihydre2H-3,1-benzoxa~in-2-one derivatives were synthesized and tested for pharmacological activity. CPhenyl-6-chloro-l,4-dihydro-2H-3,l-benzoxazin-2-one (Compound 4) exhibited anticonvulsant activity against chemically and electrically induced seizures and low acute toxicity in mice. St
Synthetic, Biocatalytic Acetylation and Antituberculosis Activity Evaluation Studies on (.+-.)-4-Alkyl-3,4-dihydro-3-ω-hydroxyalkyl-2H-1,3-benzoxazines.
✍ Scribed by Ashok K. Prasad; et al. et al.
- Publisher
- John Wiley and Sons
- Year
- 2003
- Weight
- 117 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0931-7597
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## Abstract An application of ultrasonic irradiation in the one‐pot synthesis of __N__‐acetyl‐2‐aryl‐1,2‐dihydro‐(4__H__)‐3,1‐benzoxazin‐4‐ones from the condensation reaction between aromatic aldehydes and anthranilic acid in the presence of excess amount of acetic anhydride has been explored. The
In addition to the parent compounds, nine methyl-substituted l,Mibydro-4H-3,l-benzoxazines with and without N-methyl substitution were prepared. The chain tautomer could only be detected in the case of 1,2-dihydro-2+ nitrophenyl)-4H-3,1-benzoxazine in solution. The configurational and conformational