Synthetic approaches to 4-spiro-2-hydroxytetronic acids
โ Scribed by Witiak, Donald T.; Tehim, Ashok K.
- Book ID
- 111952585
- Publisher
- American Chemical Society
- Year
- 1987
- Tongue
- English
- Weight
- 621 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
Differsnr/y substituted #~(si/ylmcthyl)-2-~etidinones were prepared siwting form the corresponding 4~aCeiQxy-Z-aretidinQnirs with sily/methylmagnesium chlarides. The same kind of /Macrams were synthesjxed "via" cycloaddition of a//yManes and ch/orosu/fonyl isacyanate (CS/).
A new synthetic pathway to spiro[cyclohexane-1,3 0 -indoline]-2 0 ,4-diones was found starting from 3-chloromethylene-2-indolones 1 and Danishefsky's diene 2. Their synthesis consists of several steps involving the formation of the cycloadducts, the 6-chloro-4-trimethylsilyloxy-2-methoxyspiro[cycloh