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Synthetic and biological studies on a cyclopolypeptide of plant origin

โœ Scribed by Rajiv Dahiya; Akhilesh Kumar

Book ID
111842323
Publisher
SP Zhejiang University Press
Year
2008
Tongue
English
Weight
477 KB
Volume
9
Category
Article
ISSN
1673-1581

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We have previously demonstrated that a 23-amino acid peptide derived from the V3 loop of the surface glycoprotein of the HIV-1 strain MN is able to bind CD4 and to enhance HIV-1 infection. Further studies have suggested that the peptide/CD4 interaction induces an increase in both CD4 expression and