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Synthesis, studies and in-vitro antibacterial activity of N-substituted 5-(furan-2-yl)-phenyl pyrazolines

โœ Scribed by Rani, Mamta; Yusuf, Mohamad; Khan, Salman Ahmad; Sahota, P.P.; Pandove, G.


Book ID
121480570
Publisher
Elsevier
Year
2015
Tongue
English
Weight
510 KB
Volume
8
Category
Article
ISSN
1878-5352

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6-[5-(4-Amidinophenyl)furan-2-yl]nicotinamidine-d 4 (5) was synthesized from 6-[5-(4-cyanophenyl)furan-2-yl]nicotinonitrile-d 4 (3), through the bis-O-acetoxy-amidoxime followed by hydrogenation. Compound 3 was prepared from 6-(furan-2-yl)nicotinonitrile by a Heck coupling reaction with 4-bromobenzo