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Synthesis and in-vitro-antibacterial activity of [5-(furan-2-yl)-phenyl]-4,5-carbothioamide-pyrazolines

โœ Scribed by Mamta Rani; Mohamad Yusuf; Salman Ahmad Khan


Book ID
118480799
Publisher
Elsevier
Year
2012
Tongue
English
Weight
412 KB
Volume
16
Category
Article
ISSN
1319-6103

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โœ Mohamed A. Ismail; David W. Boykin ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 136 KB ๐Ÿ‘ 1 views

6-[5-(4-Amidinophenyl)furan-2-yl]nicotinamidine-d 4 (5) was synthesized from 6-[5-(4-cyanophenyl)furan-2-yl]nicotinonitrile-d 4 (3), through the bis-O-acetoxy-amidoxime followed by hydrogenation. Compound 3 was prepared from 6-(furan-2-yl)nicotinonitrile by a Heck coupling reaction with 4-bromobenzo