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Synthesis, structure elucidation and antibacterial activity of 6-ethyl-6,9-dihydro-9-oxopyrazolo[3,4-f]quinoline-8-carboxylic acid

✍ Scribed by Thomas J. Schwan; Raymond Freedman; Jay R. Pollack


Book ID
112127237
Publisher
Journal of Heterocyclic Chemistry
Year
1983
Tongue
English
Weight
253 KB
Volume
20
Category
Article
ISSN
0022-152X

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## Abstract Alkylation of 6,7‐difluoro‐4‐hydroxyquinoline‐3‐carboxylic acid ethyl ester with substituted‐benzyl chlorides gave 1‐(substituted‐benzyl)‐6,7‐difluoro‐1,4‐dihydro‐4‐oxoquinoline‐3‐carboxylic acid ethyl esters. Their treatment with piperazine or __N__‐methylpiperazine in pyridine yielded