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Synthesis, SAR, and antitumor properties of diamino-C,N-diarylpyrimidine positional isomers: inhibitors of lysophosphatidic acid acyltransferase-β

✍ Scribed by Baoqing Gong; Feng Hong; Cory Kohm; Scott Jenkins; John Tulinsky; Rama Bhatt; Peter de Vries; Jack W Singer; Peter Klein


Book ID
108073251
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
278 KB
Volume
14
Category
Article
ISSN
0960-894X

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✍ Dr. André De Bruyn; Dirk Van Haver; Fernand Lambein; Berhanu M. Abegaz 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 760 KB

The 'H and 13C NMR data of DAPRO, a-and p-ODAP were measured at varying pH values and the physical relevance of these data was studied. As a potential way to detoxify the neurotoxin p-ODAP, its isomerization was studied at room temperature and at 60°C. An unknown hydrolysate is identified as