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Chemical properties of the natural neurotoxin of Lathyrus sativus 3-N-oxalyl-2,3-diamino-propanoic acid (β-ODAP), its nontoxic 2-N-oxalyl isomer, and its hydrolysis product 2,3-diamino-propanoic acid (DAPRO) by 1H- and 13C-NMR spectroscopy

✍ Scribed by Dr. André De Bruyn; Dirk Van Haver; Fernand Lambein; Berhanu M. Abegaz


Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
760 KB
Volume
1
Category
Article
ISSN
1056-9014

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✦ Synopsis


The 'H and 13C NMR data of DAPRO, a-and p-ODAP were measured at varying pH values and the physical relevance of these data was studied. As a potential way to detoxify the neurotoxin p-ODAP, its isomerization was studied at room temperature and at 60°C. An unknown hydrolysate is identified as