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Synthesis, Rotamer Orientation, and Calcium Channel Modulation Activities of Alkyl and 2-Phenethyl 1,4-Dihydro-2,6-dimethyl-3-nitro-4-(3- or 6-substituted-2-pyridyl)-5-pyridinecarboxylates †

✍ Scribed by Iqbal, Nadeem; Akula, Murthy R.; Vo, Dean; Matowe, Wandikayi C.; McEwen, Carol-Anne; Wolowyk, Michael W.; Knaus, Edward E.


Book ID
121011125
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
145 KB
Volume
41
Category
Article
ISSN
0022-2623

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ChemInform Abstract: Synthesis and Calci
✍ R. MIRI; S. E. HOWLETT; E. E. KNAUS 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

Synthesis and Calcium Channel Modulating Effects of Isopropyl 1,4-Dihydro-2,6-dimethyl-3-nitro-4-(thienyl)-5-pyridinecarboxylates. -The synthesis of the title compounds (IV) (6 examples) by a modified Hantzsch reaction is reported. All the compounds exhibited only weak calcium channel antagonist act