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Synthesis, resolution and absolute configuration of the diol metabolites of precocene I

✍ Scribed by Richard C. Jennings

Publisher: Elsevier Science
Year: 1982
Tongue: French
Weight: 245 KB
Volume: 23
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)87434-1

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✦ Synopsis

All four stereoisomers of precocene I 3,4-dihydrodiol have been prepared and their absolute configurations assigned by the exciton chirality method.

The chromene derivatives, precocene I (11 and 11(2), which occur naturally in some Ageratum species, induce premature metamorphosis or sterility when administered to certain sensitive species of insect'.

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