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Synthesis, Physicochemical Properties, and Evaluation of N -Substituted-2-alkyl-3-hydroxy-4(1 H )-pyridinones †

✍ Scribed by Rai, Bijaya L.; Dekhordi, Lotfollah S.; Khodr, Hicham; Jin, Yi; Liu, Zudong; Hider, Robert C.


Book ID
120196978
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
217 KB
Volume
41
Category
Article
ISSN
0022-2623

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Synthesis of 6-Substituted-3-hydroxy-4(1H)-pyridinones: Oxidation-Michael Addition of 3-Hydroxy-4(1H)-pyridinones. -The oxidation of pyridinones of type (I) with Ag 2 O involving alcohols (II) is reported for the first time. The resulting pyridinediones subsequently undergo Michael addition with thi