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Synthesis, photochemical reactions, and tubulin binding of novel photoaffinity labeling derivatives of colchicine

✍ Scribed by Staretz, Marianne E.; Hastie, Susan Bane


Book ID
120084378
Publisher
American Chemical Society
Year
1993
Tongue
English
Weight
520 KB
Volume
58
Category
Article
ISSN
0022-3263

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Colchicine Models: Synthesis and Binding
✍ Yoshikuni Itoh; Arnold Brossi; Ernest Hamel; Chii M. Lin πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 German βš– 769 KB

Synthesis of tetramethoxybiphenyl21 was accomplished from 4-phenylcyclohexane-1,3-dione 13 by aromatization to biphenyl 19 and reductive removal of the phenolic OH group as phenyltetrazolyl ether. Tetramethoxybiphenyls 34 and 40 were obtained from 4-phenylcyclohexenone 26 via ester 27. The tetrameth