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Synthesis ofrac-Bisabola-3(15),10-dien-7-ol

✍ Scribed by Weyerstahl, Peter ;Schlicht, Volker

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
199 KB
Volume
1997
Category
Article
ISSN
0947-3440

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✦ Synopsis

Abstract

1‐Acetyl‐4‐methylenecyclohexane (6) was obtained from ethyl 4‐methylenecyclohexane carboxylate (2), by DIBAH reduction (→ 4), Grignard reaction (→ 5) and oxidation. A further Grignard reaction furnished the rac‐bisabola‐3(15),10‐dien‐7‐ol (1), which we isolated recently from Vetiver oil. Its odor is mainly aldehydic (fatty, floral).

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