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Synthesis ofN-substituted 2-(5,6,7,8-tetrafluoro-4-oxo-1,4-dihydroquinolin-3-yl)glyoxylic acids

✍ Scribed by G. A. Obanin; A. S. Fokin; Ya. V. Burgart; O. V. Ryzhkov; Z. E. Skryabina; V. I. Saloutin; O. N. Chupakhin

Book ID
105596155
Publisher
Springer
Year
2000
Tongue
English
Weight
386 KB
Volume
49
Category
Article
ISSN
1573-9171

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The formylation reaction of norfloxacin with __N__,__N__-dimethylformamide (DMF) gives the title compound, C~17~H~18~FN~3~O~4~. In the structure, molecules are connected __via__ weak Cβ€”H...O, Cβ€”H...Ο€ and π–π interactions [perpendicular distance 3.423β€…Γ… and centroid–centroid distance 3.8141β€…Γ…].