Synthesis of [77Br] 5,7-dibromo-4-oxo-1,
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F. Dumont; G. Slegers
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Article
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1996
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John Wiley and Sons
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French
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The synthesis of [77Br] 5,7-dibromo-4-oxo-1,4-dihydroquinoline-2-carboxylic acid is described. The labelling is performed in order to obtain a tracer for SPECT studies of the Nmethyl-D-aspartate receptor in human brain. Radiosynthesis was carried out using a nonisotopic nucleophilic halogen exchange