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Synthesis of γ-lactone derivatives as a key intermediate for the spiroketal fragment in calyculin A

✍ Scribed by Mototsugu Kabeya; Yasumasa Hamada; Takayuki Shioiri

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
400 KB
Volume
53
Category
Article
ISSN
0040-4020

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✦ Synopsis

A simple and safe route to the D-xylone-l,4-1actone derivative 3, a key intermediate for the synthesis of the spiroketal fragment in calyculin A (1) has been explored without the use of hazardous diazomethane on a large scale.

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