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Synthesis of β-Amino Alcohols from Methyl Epoxy Stearate

✍ Scribed by Singh, Sukhprit; Kamboj, Raman


Book ID
118037339
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
261 KB
Volume
49
Category
Article
ISSN
0888-5885

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Synthesis of chiral, nonracemic methylen
✍ Julie Ince; Tracey M. Ross; Michael Shipman; David S. Ennis 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 626 KB

An efficient three step process for the synthesis of chiral, nonracemic methyleneaziridines derived from homochiral [3-amino alcohols is described. Methyleneaziridines 4a-e produced using this chemistry have been shown to possess high enantiomeric purities (>\_ 95%ee).