Synthesis of α-Amino-γ-halogenobutyric Acids. A New Synthesis of DL-Homoserine
✍ Scribed by Frankel, Max; Knobler, Y.
- Book ID
- 121424299
- Publisher
- American Chemical Society
- Year
- 1958
- Tongue
- English
- Weight
- 424 KB
- Volume
- 80
- Category
- Article
- ISSN
- 0002-7863
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📜 SIMILAR VOLUMES
Various N-protected amino acids bearing an enol ether side chain were synthesized by a new method allowing a great versatility in the introduction of both the N-protective groups and the enol ether moieties. This method deals with a Wittig-Homer condensation to afford the a$-dehydro homoserine ether
A lacile slereoselcctive melhod Ior the synthesis of y-substituted, y-mnino acids from of amino acids was developed. The key step of the procedurc is complete reduction of Ihe keto functionality of ot-~unino acyl Meldruln's acid by sodium acetoxyborohydride. The resulting amino alkyl Meldrum's acid