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Synthesis of α-Amino Acids by Umpolung of Weinreb Amide Enolates

✍ Scribed by Sebastian Hirner; Donata K. Kirchner; Peter Somfai

Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
186 KB
Volume
2008
Category
Article
ISSN
1434-193X

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✦ Synopsis

Abstract

An efficient and diastereoselective synthesis of α‐amino acids from readily available starting materials has been developed. The key feature of this reaction is an umpolung of a glycine‐derived enolate, providing an alternative approach for the synthesis of α‐amino acids. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)

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✍ Sebastian Hirner; Peter Somfai 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 51 KB

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