Hydrolysis of secologanin ethylene acetal at pH 7 resulted in stereoselective aldol cyclisation to a cyclohexene aldehyde, which, on reductive amination and cyclisation with tryptamine aorded (^)-3-iso-19,20dehydro-b-yohimbine, converted into various normal and pseudo isomers of yohimbine.
β¦ LIBER β¦
Synthesis of yohimbines. 4. Synthesis of (.+-.)-3-epi-.alpha.-yohimbine and (.+-.)-3,17-epi-.alpha.-yohimbine. Carbon-13 NMR investigation of yohimbine stereoisomers
β Scribed by Honty, Katalin; Baitz-Gacs, Eszter; Blasko, Gabor; Szantay, Csaba
- Book ID
- 126197435
- Publisher
- American Chemical Society
- Year
- 1982
- Tongue
- English
- Weight
- 519 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0022-3263
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