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Synthesis of Xanthone-O-Glycosides. II.. Synthesis of 1-O-β-glycosides

✍ Scribed by V. Mohan Chari; Rosalinde Klapfenberger; Hildebert Wagner; Kurt Hostettmann

Publisher
John Wiley and Sons
Year
1979
Tongue
German
Weight
359 KB
Volume
62
Category
Article
ISSN
0018-019X

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✦ Synopsis

Abstract

Several naturally occurring xanthone‐1‐O‐glycosides have been synthesized in order to study monoamine oxidase (MAO) inhibition structure‐activity relationships. The syntheses also confirmed the structures as 1‐β‐D‐glucosyloxy‐3‐hydroxy‐5‐methoxyxanthone (Canscora decussata SCHULT.), 1‐O‐β‐primeverosyl‐3, 7, 8‐trimethoxyxanthone (decussatin‐1‐O‐primeveroside, Gentiana verna L.) and 1‐O‐β‐primeverosyl‐3, 8‐dimethoxy‐7‐hydroxyxanthone (gentiacaulein‐1‐O‐β‐primeveroside, Gentiana verna L.).

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