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Synthesis of various 5-substituted uracils

✍ Scribed by Dan Peters; Anna-Britta Hörnfeldt; Salo Gronowitz


Book ID
112129855
Publisher
Journal of Heterocyclic Chemistry
Year
1990
Tongue
English
Weight
653 KB
Volume
27
Category
Article
ISSN
0022-152X

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Novel 1-(dihydroxypropyl)-5-substituted uracils were synthesized in the reaction of 1-(4-nitrophenyl)-5-substituted uracil derivatives with appropriate aminopropanediols under mild conditions. In the case of 3-amino-1,2-propanediol both racemic and enantiomerically enriched products were obtained. T