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Synthesis of variants of 5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine

✍ Scribed by Shih-Hsi Chu; Zhi-Hao Chen; Zum-Yao Weng; Elizabeth C. Rowe; Edward Chu; Ming-Yu Wang Chu


Book ID
112128403
Publisher
Journal of Heterocyclic Chemistry
Year
1986
Tongue
English
Weight
509 KB
Volume
23
Category
Article
ISSN
0022-152X

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## Abstract A uridine phosphorylase inhibitor, 5‐benzylacyclouridine (BAU), has been utilized as biochemical modulator of 5‐fluorouracil (5‐FU) anti‐tumor activity in a murine tumor model. The effect of BAU on 5‐FU metabolism has been evaluated using __in vitro__ and __in vivo__ ^19^F NMR spectrosc