## Abstract For Abstract see ChemInform Abstract in Full Text.
Synthesis of Unsaturated Polyhydroxycarboxylic Acids as Structural Analogues of an Arachidonic Acid Metabolite
β Scribed by Aleksander G. Tolstikov; Oleg F. Prokopenko; Leonard M. Khalilov; Leonid V. Spirikhin; Arnold A. Berg; Vilina R. Sultanmuratova; Genrikh A. Tolstikov
- Book ID
- 111729295
- Publisher
- Royal Society of Chemistry
- Year
- 1991
- Tongue
- English
- Weight
- 152 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0959-9436
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π SIMILAR VOLUMES
## Abstract The usefulness of hexaβ2,5βdiynβ1βol as an intermediate in the synthesis of arachidonic acid, polyβyn alcohols and docosaβ4,7,10,13,16,19βhexaynoic acid is demonstrated. Difficulties in the partial reduction of the latter product to the corresponding all cisβhexaenoic acid are described
The enantiomers R-and S-3-hydroxyeicosatetraenoic acid lla, lib were synthesized from coupling of a chiral aldehyde 7 with a Wittig salt 4, which were derived from 2-deoxy-D-ribose and arachidonic acid, respectively.