## Abstract Reaction of 6โchloropyrimidines with diethyl [(2โaminoethoxy)methyl]phosphonate allows for a ready access to acyclic nucleoside phosphonates. A series of 5โsubstituted pyrimidines bearing a phosphonate side chain at position 6 were synthesized and tested against herpes simplex viruses (
Synthesis of Unsaturated Phosphonates as Acyclic Nucleosides Analogues
โ Scribed by Brel, Valery K.
- Book ID
- 120449733
- Publisher
- Taylor and Francis Group
- Year
- 2002
- Tongue
- English
- Weight
- 46 KB
- Volume
- 177
- Category
- Article
- ISSN
- 1042-6507
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๐ SIMILAR VOLUMES
Acyclic carba-nucleoside phosphonates, modelled on natural Wittig-Horner-Emmons reaction with the anion of tetraisopropyl methylenebisphosphonate gave, after deoxyribonucleotides have been prepared starting from DNA nucleobases and tert-butyl acrylate. The products deprotection, the desired 4-hydrox
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a โFull Textโ option. The original article is trackable v