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Synthesis of two bi-functional ligands for the QUEST three-hybrid system

✍ Scribed by Stephen J Baker; Steven M Firestine; David Smithrud; Frank Salinas; Stephen J Benkovic

Book ID: 104210776
Publisher: Elsevier Science
Year: 2000
Tongue: French
Weight: 161 KB
Volume: 41
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)01202-8

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✦ Synopsis

The synthesis is described for two bi-functional ligands (1) and ( 2) that have been used as chemical inducers of dimerization for QUEST, 1 a three-hybrid system designed to detect novel enzyme activity in vivo.

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