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Synthesis of tritiated β-(S-benzylmercapto)-β,β-cyclopentamethylene propionic acid

✍ Scribed by Scott W. Landvatter; J. Richard Heys


Publisher
John Wiley and Sons
Year
1987
Tongue
French
Weight
249 KB
Volume
24
Category
Article
ISSN
0022-2135

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A rapid and easy synthesis of tritium-labelled 8-iodopenicillanate, an efficient inactivator of serine B-lactamase, is described. This method involves only three reaction steps after the introduction of the label in the molecule with an overall yield of 16 % .