Synthesis of Trifluoromethanesulfonic Acid from CHF 3
β Scribed by Mukhopadhyay, Sudip; Bell, Alexis T.; Srinivas, R. Vijay; Smith, Gary S.
- Book ID
- 120082988
- Publisher
- American Chemical Society
- Year
- 2004
- Tongue
- English
- Weight
- 77 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1083-6160
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A general method is described for forming peptide amides by cleavage from benzhydrylaminesin using a mixture of trifluoromethanesulfonic acid, thioanisole and trifluoroacetic acid. This procedure gives comparable results to cleavage by liquid hydrogen fluoride.