𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of trideuterated stanozolol labelled selectively at the 17-methyl group

✍ Scribed by D. Johnston; K. Henderson

Publisher
John Wiley and Sons
Year
1983
Tongue
French
Weight
185 KB
Volume
20
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

✦ Synopsis

A synthetic procedure for stanozolol-d3 labelling was achieved by .the Grignard reaction of androstan-3p -01 -1 7one with deuterium labelled methyl magnesium iodide (CD Mg I). The synthesis was achieved in five steps from A5-androstan-3-p-ol-17-one in an overall yield of 15%. The procedure resulted in a product which was selectively deuterated and chemically pure.

📜 SIMILAR VOLUMES

Stereospecific synthesis of Δ24-sterols
Stereospecific synthesis of Δ24-sterols labelled on the 26- or 27-methyl group
✍ F. Nicotra; F. Ronchetti; G. Russo 📂 Article 📅 1978 🏛 John Wiley and Sons 🌐 French ⚖ 342 KB

## Abstract A convenient synthesis of Δ^24^‐sterols labelled on the 26‐ or 27‐methyl group, exemplified by the synthesis of [26‐^3^H]‐lanosterol, is described. Oxidation of lanosteryl acetate with SeO~2~ gives 3β‐acetoxylanosta‐8, 24‐dien‐26‐al; this is reduced to the corresponding labelled alcohol

The synthesis of aliphatic and aromatic
The synthesis of aliphatic and aromatic hydrocarbons containing methyl groups labelled with 11C
✍ B. Långstro̊m; S. Sjöberg 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 391 KB

## Abstract The synthesis of [1‐^11^C]pentane, [1‐^11^C]nonane, [1‐^11^C]‐ undecane, 2‐[^11^ C]methyl‐naphthalene and [^11^C]methyl‐benzene (toluene) are reported. The hydrocarbons were prepared by the coupling reaction between [^11^C]methyl iodide and the appropriate lithium organocuprate. Toluene

Synthesis of mitomycin C labeled with mo
Synthesis of mitomycin C labeled with mono-tritium at the C6 - methyl position
✍ Yutaka Kanda; Shiro Akinaga; Masaji Kasai 📂 Article 📅 1990 🏛 John Wiley and Sons 🌐 French ⚖ 165 KB

## Abstract A first preparation of mitomycin C specifically labeled with mono‐tritium at the C6‐methyl position is described. The key intermediate in the synthesis, 7,7‐ethylenedioxy‐6‐methylenemitosane (5) was made by treating 7,7‐ethylenedioxy‐6‐phenylselenomitosane (4) with meta‐chloroperbenzoic

Abstracts of the 17th International Isot
Abstracts of the 17th International Isotope Society (UK group) Symposium Synthesis and Applications of Labelled Compounds 2008
✍ F. I. Aigbirhio; P. Allen; S. Andersson; M. Anton; D. Barron; A. J. Bloom; N. P. 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 French ⚖ 319 KB 👁 1 views

The organic chemistry of sulfur is a vast field, forming a major branch of modern organic chemistry that is undergoing continual development and expansion. The aryl-sulfur linkage, Ar-S, at its manifold oxidation levels is encountered frequently in pharmaceutical motifs, and comprises an important e