Abstracts of the 17th International Isotope Society (UK group) Symposium Synthesis and Applications of Labelled Compounds 2008

✍ Scribed by F. I. Aigbirhio; P. Allen; S. Andersson; M. Anton; D. Barron; A. J. Bloom; N. P. Botting; W. Brandau; L. Brichard; J. A. Brown; R. T. Brown; K. M. Cable; M. Caffrey; M. A. Carroll; D. J. Chaplin; V. Coissard; F. Cuyckens; O. Demmer; I. Dijkgraaf; A. M. Dyke; D. M. Gill; K. A. Hall; A. J. Hester; M. Hickey; S. Irvine; C. Janssen; W. J. Kerr; H. Kessler; L. P. Kingston; C. Landreau; K. W. M. Lawrie; G. Lloyd-Jones; H. Loaring; W. J. S. Lockley; L. J. Marshall; B. Mo; J. D. Moseley; V. L. Murrell; G. N. Nilsson; R. Oekonomopulos; K. G. Pinney; S. Pleasance; S. Raddatz; A. T. Rees; R. G. Reid; J. S. Renny; F. Robert; D. Rustidge; U. Schumacher; D. M. Schwaiger; S. Sharma; D. Soloviev; A. C. Spivey; M. Sriram; J. Thijssen; C.-C. Tseng; W. Verluyten; F. Viton; M. Vliegen; H. Weldon; H-J. Wester; D. J. Wilkinson; J. M. J. Williams; G. Williamson; C. L. Willis; R. Yan

• Publisher: John Wiley and Sons
• Year: 2009
• Tongue: French
• Weight: 319 KB
• Volume: 52
• Category: Article
• ISSN: 0022-2135
• DOI: 10.1002/jlcr.1590

✦ Synopsis

The organic chemistry of sulfur is a vast field, forming a major branch of modern organic chemistry that is undergoing continual development and expansion. The aryl-sulfur linkage, Ar-S, at its manifold oxidation levels is encountered frequently in pharmaceutical motifs, and comprises an important element of organosulfur chemistry. There are numerous methods for the preparation of Ar-S species each with its own benefits and problems. Phenols are attractive precursors as many are readily available or readily prepared. We have been exploring the mechanism of two Ar-S generating reactions. The first is quite well established (1-2) first reported in 1965, 1 and known as the Newman-Kwart rearrangement, 2 whilst the second (3-4) is much more recent and is referred to as the anionic thia-Fries rearrangement 3 209 Abstracts