work in our laboratories has focused on developing simple conditions for insertion of isotopically useful 'X' moieties into organic substrates ('R') of value to society. The overall concept is illustrated for biologically important radioisotopes but the corresponding stable isotopes have also been i
17th workshop of the international isotope society – central european division. The synthesis and applications of isotopes and isotopically labelled compounds
✍ Scribed by Peter Wiegerinck
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- French
- Weight
- 278 KB
- Volume
- 54
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
The general treatment paradigm in modern medicine has shifted from a 'one size fits all' approach towards an individualized patient based therapy.
An efficient targeted therapy approach requires powerful diagnostic imaging tools in order to: detect a disease early; to stratify the patient's personal disease status; to select a tailor-made therapy; dose at the right time; and to monitor therapy response early.
The fusion of Positron Emission Tomography (PET) with X-ray Computed Tomography (CT) offers a powerful opportunity to gain such information and forms a strong basis for personalized medicine.
A pre-requisite is the availability of highly selective molecular imaging (MI) PET-tracers designed to target disease specific pathways and pathologies.
BSP uniquely combines: 1) broad disease know-how; 2) expertise in compound generation; 3) radiochemistry; 4) pre-clinical compound evaluation; 5) a leading position in diagnostic imaging.
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