Synthesis of trichostatin a, a potent differentiation inducer of friend leukemic cells, and its antipode

✍ Scribed by Kenji Mori; Koshi Koseki

• Book ID: 104204937
• Publisher: Elsevier Science
• Year: 1988
• Tongue: French
• Weight: 595 KB
• Volume: 44
• Category: Article
• ISSN: 0040-4020
• DOI: 10.1016/s0040-4020(01)89789-1

✦ Synopsis

Both the enantiomers of tnchostatic acid (1, 98% eo6.) and trichostatl.n A (2, 93% eo6.) were synthesized employwg methyl (R)-or (S)-3-hydroxy-2-methylpropanoate as a starting material.

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