## Abstract The total synthesis of thymosin β~4~ by means of classical methods using three protected fragments is described. For their syntheses the Z/__t__Bu strategy and temporary phenyl ester protection of the C‐terminal carboxyl were used. Various coupling procedures were applied in order to op
✦ LIBER ✦
SYNTHESIS OF THYMOSIN β4
✍ Scribed by Wang, S.S. ;Wang, B.S.H. ;Chang, J.K. ;Low, T.L.K. ;Goldstein, A.L.
- Book ID
- 115097796
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 191 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0367-8377
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Total Synthesis of Thymosin β~4~, 1. – Conventional Synthesis of the Fragment [11–19] of Thymosin β~4~ As part of the total synthesis of thymosin β~4~ two synthetic pathways for the synthesis of the thymosin β~4~ fragment [11–19] are described. The side‐chain functions are protected by __tert__‐but