𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of thymidine from 5-iodo-2′-deoxyuridine

✍ Scribed by P. Herdewijn; L. Kerremans; P. Wigerinck; F. Vandendriessche; A. Van Aerschot

Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
206 KB
Volume
32
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Synthesis of 5-deuteromethyl-2′-deoxyuri
Synthesis of 5-deuteromethyl-2′-deoxyuridine (thymidine-α,α,α-d3) and related compounds
✍ C.-Y. Shiue; A. P. Wolf; D. N. Slatkin 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 French ⚖ 289 KB

## Abstract Thymine‐α,α,α‐d~3~ (**4**) was synthesized from perdeuterated methyl iodide and pyrimidine‐lithium. Thymidine‐α,α,α‐d~3~ (**8**) was then synthesized by coupling compound **4** with 1α‐chloro‐2‐deoxy‐3,5‐bis(p‐toluoyl)‐α‐D‐ribofuranosyl chloride in the presence of Friedal‐Crafts catalys

Continuous spectrophotometric assay of t
Continuous spectrophotometric assay of thymidine phosphorylase using 5-nitro-2′-deoxyuridine as substrate
✍ Yusuke Wataya; Daniel W. Santi 📂 Article 📅 1981 🏛 Elsevier Science 🌐 English ⚖ 231 KB

A continuous spectrophotometric assay of deoxythymidine (dThd) phosphorylase is reported which monitors conversion of Snitro-2'-deoxyuridine to S-nitrouracil. The reaction is accompanied by a large increase in absorbance (AE = 10') in a region of the visible spectrum (350 nm) which is free from inte