SYNTHESIS OF THIENO(2,3-b)THIOPHENES AND RELATED STRUCTURES
β Scribed by El-shafei, A. K.; Abdel-ghany, H. A.; Sultan, A. A.; El-saghier, A. M. M.
- Book ID
- 119967111
- Publisher
- Taylor and Francis Group
- Year
- 1992
- Tongue
- English
- Weight
- 470 KB
- Volume
- 73
- Category
- Article
- ISSN
- 1042-6507
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π SIMILAR VOLUMES
Synthesis of Polyfunctionalized Thiophenes and Enediynes via Ring-Opening Reactions of 3-Lithiated Thieno[2,3-b](and [3,2b])thiophenes , 3,4-Dilithiated Thieno[2,3-b]thiophenes and3,6-Dilithiated Thieno[3,2-b]thiophenes. -Solutions of title lithiated thienothiophenes are obtained from the correspond
Rust) 160 (calc. 165.2); Amax= 247mp (log⬠= 3.89);222mp (log E = 4.38) [3]) is obtained in 79 % yield.
A series of the title compounds were prepared for evaluation as inhibitors of carbonic anhydrase II. Oxidation of 5-substituted thieno[2,3-b]thiophene-2-sulfonamides provided the first examples of thiophene[2,3-b]thiophene-2-sulfonamide 6,6-dioxides. These cyclic vinyl sulfones readily underwent add