Donor–acceptor thieno[2,3-b]thiophene systems: synthesis and structural study of 3-anisyl-4-pyridyl(pyridinium) thieno[2,3-b]thiophenes
✍ Scribed by Sabir H Mashraqui; Mohamed Ashraf; Harini Hariharasubrahmanian; Richard M Kellogg; A Meetsma
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 199 KB
- Volume
- 689
- Category
- Article
- ISSN
- 0022-2860
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A series of the title compounds were prepared for evaluation as inhibitors of carbonic anhydrase II. Oxidation of 5-substituted thieno[2,3-b]thiophene-2-sulfonamides provided the first examples of thiophene[2,3-b]thiophene-2-sulfonamide 6,6-dioxides. These cyclic vinyl sulfones readily underwent add