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Synthesis of the tangutorine skeleton

✍ Scribed by Mathias Berner; Arto Tolvanen; Reija Jokela


Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
178 KB
Volume
40
Category
Article
ISSN
0040-4039

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✦ Synopsis


The ring system of the novel indole alkaloid tangutorine (1) has been synthesized via the Fry reaction. The final key steps were an oxidation/reduction procedure or alternatively, an epimerization sequence. Conformational and stereochemical aspects of the skeleton are discussed.


πŸ“œ SIMILAR VOLUMES


Synthesis of Tangutorine.
✍ Tse-Lok Ho; Chun-Kuei Chen πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons βš– 18 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Synthesis of Tangutorine
✍ Tse-Lok Ho; Chun-Kuei Chen πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons 🌐 German βš– 71 KB

Tangutorine (1) in the racemic form has been assembled from tryptamine and aldehyde 3. The synthetic design was based on uncovering a hidden symmetry in the nontryptamine portion of the norketone 2. A five-step process with an overall yield of 7% was developed in which 2 was transformed into the tar

First total synthesis of (Β±)-tangutorine
✍ Tiina Putkonen; Arto Tolvanen; Reija Jokela πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 French βš– 66 KB
ChemInform Abstract: First Total Synthes
✍ Tiina Putkonen; Arto Tolvanen; Reija Jokela πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 30 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v