## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
First total synthesis of (±)-tangutorine
✍ Scribed by Tiina Putkonen; Arto Tolvanen; Reija Jokela
- Publisher
- Elsevier Science
- Year
- 2001
- Tongue
- French
- Weight
- 66 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4039
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Tangutorine (1) in the racemic form has been assembled from tryptamine and aldehyde 3. The synthetic design was based on uncovering a hidden symmetry in the nontryptamine portion of the norketone 2. A five-step process with an overall yield of 7% was developed in which 2 was transformed into the tar
The ring system of the novel indole alkaloid tangutorine (1) has been synthesized via the Fry reaction. The final key steps were an oxidation/reduction procedure or alternatively, an epimerization sequence. Conformational and stereochemical aspects of the skeleton are discussed.