## Abstract Synthesis of the DEF‐ring terpenoid fragment of terpendole E, an Eg5 inhibitor, is described. The DE‐ring was constructed by a modification of Barrero's radical cyclization. The F‐ring tetrahydropyran was then constructed by acid‐induced cyclization of an epoxy alcohol, which was prepar
Synthesis of the right hand fragment of tylonolide
✍ Scribed by Linda D.-L. Lu
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- French
- Weight
- 256 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
The synthesis of the lactonic thioester 5, corresponding to the C(l)-C( 9) fragment of tylonolide hemiacetal, via the bicyclic ester 5 , is described.
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