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Enantiospecific and diastereoselective synthesis of C11-C17 fragment of tylonolide from “asymmetrized tris (hydroxymethyl)methane”

✍ Scribed by Giuseppe Guanti; Luca Banfi; Chiara Ghiron; Enrica Narisano


Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
282 KB
Volume
32
Category
Article
ISSN
0040-4039

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✍ Keisuke Suzuki; Katsuhiko Tomooka; Takashi Matsumoto; Eiji Katayama; Gen-ichi Ts 📂 Article 📅 1985 🏛 Elsevier Science 🌐 French ⚖ 271 KB

Two chiral intenediates, C(l)-C( 9) and C(llI-Cc171 portions of protomycinolide IV, were synthesized both from (Sl-ethyl lactate via asymmetric pinacoZ-type rearrangement folZowed b2 diastereoselective reactions on cc-methyl-B,y-unsaturated carbonyl compounds.