Synthesis of the racemic alkaloid diptaline
β Scribed by A. G. Tolstikov; L. A. Biktimirova; O. V. Tolstikova; V. S. Shmakov; E. M. Vyrypaev; G. A. Tolstikov
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 280 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0009-3130
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The total synthesis of the SC&&& alkaloids mesembranone, joubertinamine and epijoubertinamine via the intramolecular cyclization of an enone to a benzensulfon amide grouping under the conditions of a dissolving metal reduction is described.
## Abstract magnified image Anatabine is a major alkaloid in __Nicotiana tabacum__ and its isomer, isoanatabine, was recently found in a marine worm. Reduction of 1βmethylpyridinium iodide with sodium borohydride gave 1βmethylβ3βpiperideine, which was transformed with hydrogen peroxide into the __N