NG-Monomethylagmatine, a decarboxylation product of NG-monomethyl-L-arginine, has been synthesized by reacting putrescine with N,S-dimethylthiopseudouronium iodide. The structural identity of the product was confirmed by proton NMR and mass spectroscopy, and its properties were determined on thin-la
Synthesis of the putative l-arginine metabolite L-NG-hydroxyarginine
✍ Scribed by Paul L. Feldman
- Book ID
- 104225108
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- French
- Weight
- 266 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Syntheses of L-fi-hydroxyargmme (l), the putatwe b~osynthctlc precursor of mtnc oxide, and the 15N labelled analogs 9 and 10 uemg L-ormthme d+, the e~~dlmopuc srart~ng matcrlal 15 repxted The contmued progress in dcfmmg the physmloglul role of mtrx oxldc (NO) as it relates to the regulation OC cell ftmcUon and commumcanon
📜 SIMILAR VOLUMES
## Abstract N^G^‐Mono[^14^C‐methyl]‐L‐arginine was prepared in a two‐step synthesis. N,S‐dimethylthiopseudouronium iodide [methyl‐^14^C] was prepared in excellent yield and afforded the labelled amino acid on coupling with L‐ornithine.
## Abstract **BACKGROUND:** To test whether the differentiating embryo is susceptible to the teratogenic effects of the nitric oxide (NO) synthesis inhibitor N^G^‐nitro‐L‐arginine methyl ester (L‐NAME). **METHODS:** ICR‐(CD‐1) mice received a single intraperitoneal injection of L‐NAME at 90, 150, o