𝔖 Bobbio Scriptorium
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Synthesis of the potent antitumoral marine alkaloid variolin B

✍ Scribed by Pedro Molina; Pilar M. Fresneda; Santiago Delgado; Juan Antonio Bleda

Book ID
104232362
Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
64 KB
Volume
43
Category
Article
ISSN
0040-4039

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The marine natural product leucettamine B 2 has been prepared in good yield via two different routes, starting with glycine or with 3-methyl thiohydantoin, involving simple aldol condensation, and finally transamination of the thiohydantoin derivative.