✦ LIBER ✦

Synthesis of the pentacyclic core of lihouidine

✍ Scribed by Ken S. Feldman; Adiel Coca

Publisher: Elsevier Science
Year: 2008
Tongue: French
Weight: 121 KB
Volume: 49
Category: Article
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2008.01.118

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✦ Synopsis

The pentacyclic base of the sponge-derived alkaloid lihouidine has been assembled from two quinoline fragments. The key step is a nitration-promoted cyclization to form the C-C bond between the two quinoline units.

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