Synthesis of the P-sulfide derivatives of 3-phosphabicyclo[3.1.0]hexanes and 1,2-dihydrophosphinines

✍ Scribed by György Keglevich; László Tőke; Csaba Lovász; Kálmán Újszászy; Gábor Szalontai

• Publisher: John Wiley and Sons
• Year: 1994
• Tongue: English
• Weight: 604 KB
• Volume: 5
• Category: Article
• ISSN: 1042-7163
• DOI: 10.1002/hc.520050412

✦ Synopsis

Several 3-phosphabicyclo[3.1 .O] hexane 3-oxides have been transformed into the corresponding sulfides by reaction with phosphoms pentasulfide. The 3-phenyl derivative could also be prepared by deoxygenation of the oxide followed by reaction with elemental sulfur. Opening of the cyclopropane ring in phosphabicycbhexane sulfides afforded mixtures of 3-and 5methyl-l,2-dihydro-phosphinine-l -sulfides. Because of better yields, preparation of these products by thionation of the dihydrophosphinine oxides is more appropriate. The new hosphoms heterocycles have been characterized by P, I3C, and ' H NMR and mass spectral data.