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Synthesis of the optically active α-nucleic acid base substituted propanoic acids

✍ Scribed by C.G. Overberger; Ji Young Chang

Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
180 KB
Volume
30
Category
Article
ISSN
0040-4039

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✦ Synopsis

The (R)-2-(adenin-9-yl)propanoic acid 2 was prepared from adenine and (S)-ethyl lactate by using the triphenyl phosphine-diethyl azodicarboxylate system. The (R)-2-(thymin-l-yl)propanoic acid, (R)-2-(cytosin-l-yl)propanoic acid, and (R)-2-(hypoxanthin-9-yl)propanoic acid were also prepared.

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