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Synthesis of the o -Quinones and Other Oxidized Metabolites of Polycyclic Aromatic Hydrocarbons Implicated in Carcinogenesis

✍ Scribed by Harvey, Ronald G.; Dai, Qing; Ran, Chongzhao; Penning, Trevor M.


Book ID
126082630
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
177 KB
Volume
69
Category
Article
ISSN
0022-3263

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Synthesis of β€œK-region” quinones and are
✍ Hee Cho; Ronald G. Harvey πŸ“‚ Article πŸ“… 1974 πŸ› Elsevier Science 🌐 French βš– 251 KB

A new general synthesis of arene oxides recently reported' from this laboratory has allowed the synthesis of the previously inaccessible "K-region" oxides (@, ,b) of the potent carcinogens '7,12-dimethylbenzraY anthracene ('7.1 P-DMBA) and benzola] pyrene2. This approach, however, still suffers from