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Synthesis of the new ring system, Pyrazolo[3,4-d][1,3]diazepine. A novel route for the synthesis of azolo[1,3]diazepines

✍ Scribed by Oscar L. Acevedo; Steven H. Krawczyk; Leroy B. Townsend

Book ID
112127796
Publisher
Journal of Heterocyclic Chemistry
Year
1985
Tongue
English
Weight
326 KB
Volume
22
Category
Article
ISSN
0022-152X

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A facile approach to pyrazolo [4,3-e][1,4] diazepin-5,8-diones andpyrazolo[4,3-e]pyrrolo[1,2-a][1,4]diazepin-5,10-diones is reported. Strategy involved the utility of Ξ±-amino acid as a three-atom segment in the construction of diazepine skeleton on the preformed pyrazole ring.