Synthesis of the naturally occurring 6-(3-methylbuta-1,3-dienyl)indole via advanced fischer indolization of a 2-methoxyphenylhydrazone derivative
β Scribed by Hisashi Ishii; Yasuoki Murakami; Tokuo Furuse; Haruki Takeda; Nisaburo Ikeda
- Publisher
- Elsevier Science
- Year
- 1973
- Tongue
- French
- Weight
- 202 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0040-4039
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β¦ Synopsis
Recently, it was reported isolation of the first isoprenylindole, 6-(3-methylbuta-1,3dienyl)indole (l), from the seed of ?onodora tenuifozia." Now, we would like to show the synthesis of the product via the advanced Fischer indolisation of a 2-methoxyphenylhydrasone derivative.
π SIMILAR VOLUMES
We synthesized novel tetracyclic fused indole derivatives via the intramolecular Heck reaction of indole-containing Baylis-Hillman adducts in good to moderate yields.
2,2 0 -bipyridine Multi-component reaction 3-Cyanoacetyl indole Neat condition 2,2 0 -Bipyridine Microwave irradiation Cinnamils a b s t r a c t A series of 4-aryl-6-(1H-indol-3-yl)-2,2-bipyridine-5-carbonitrile derivatives were synthesized via a onepot multi-component reaction of aromatic aldehydes