Synthesis of the L-Acid (C1–C18) Fragment of Pamamycin-593 and De-N-methylpamamycin-579
✍ Scribed by Ayako Miura; Shin-ya Takigawa; Yukito Furuya; Yusuke Yokoo; Shigefumi Kuwahara; Hiromasa Kiyota
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 254 KB
- Volume
- 2008
- Category
- Article
- ISSN
- 1434-193X
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✦ Synopsis
Abstract
The L‐acid (C1–C18) fragment of pamamycin‐593 and de‐N‐methylpamamycin‐579, strong aerial mycelium‐inducers of Streptomyces alboniger, was synthesized using a cis‐selective iodoetherification and a nucleophilic addition of a cerium acetylide to an aldehyde as the key steps. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
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